The CAF Champions League weekend will open the quarter-finals with Kaizer Chiefs and Mamelodi Sundowns facing the possibility of reaching the first ever all-South African final of the continent's premier club competition.
Only once have clubs from the same country met in the final.
Egyptian heavyweights Al Ahly and Zamelek were the first clubs from the same country to square off meet in a Champions League final and this happened last year with Pitso Mosimane's team emerging victors.
With South Africa's two clubs reaching the last eight this year the order of the draw has taken shape in such a way that a Chiefs and Sundowns decider is on the cards this year.
Algerian clubs MC Alger and CR Belouizdad are also facing the same prospects as they can also meet in the final should they get past the next two stages.
That colossal mission to have two PSL clubs in the final gets underway on Saturday evening with Chiefs welcoming Tanzanian giants Simba to the FNB Stadium.
The second leg will be played the following Saturday afternoon in hostile conditions at the Benjamin Mkapa Stadium in Dar es Salaam where crowds are allowed into venues despite the corona virus.
Sundowns are already in Cairo for the blood and thunder meeting with their former coach later Saturday.
"We want to try always in every game to reflect a team that is off course tactically well drilled and well prepared and the same time the performances must always reflect the culture that we have at Mamelodi Sundowns," says Sundowns co-coach Rhulani Mokwena.
"The driving factor of that culture is relentless work ethic, and we want to try all the time to reflect that, and you can't do that if you don't have mental stability and a lot of mental balance between anxiety, fear and motivation."
The winner of the Chiefs and Simba match will come up against either MC Alger or Wydad Casablanca in the semi-finals while the Sundowns and Al Ahly winner will face Esperance or Belouizdad.
Since the continent's premier club competition adopted the Champions League format in 1997 the only countries that have had two of their clubs past the group stages are Egypt, Morocco, Tunisia, Algeria, Sudan, DR Congo and Nigeria.