Chelsea and Sevilla could not be separated in their Group E opener Stamford Bridge.
The Blues manager Frank Lampard made three changes, with goalkeeper Edouard Mendy returning in goal for his Champions League debut alongside Thiago Silva and Reece James.
There were chances at both ends through the night but sides settled for a share of the spoils in the end.
Lazio enjoyed a perfect start in Group F after thrashing Borussia Dortmund 3-1 at Stadio Olimpico.
Erling Haaland and Marco Reus returned to form an exciting front-three alongside Jadon Sancho for Dortmund while Lazio were boosted by the return of Ciro Immobile.
The hosts had a dream as Immobile fired them ahead in the sixth minute with a brilliant finish from close range after a cross by Joaquin Correa.
Correa missed a big one-on-one chance in the 22nd minute after he was denied by goalkeeper Marwin Hitz but Luiz Felipe made up for it with the second goal for Lazio a minute later with a towering header from a corner.
Haaland pulled a goal back for Lucien Favre's charges with 19 minutes remaining after a powerful strike thatgave shot-stopper Thomas Strakosha no chance. However, Jean Akpro restored the two-goal lead for the hosts in the last quarter of an hour to claim their first three points in Group F.
Rennes and Krasnodar cancelled each other out in their opener Group E after playing to a 1-1 draw at Stade de la Route de Lorient.
After a goalless first stanza, Serhou Guirassy broke the deadlock for the hosts 11 minutes into the second stanza but the lead did not last long as Cristian Ramirez got the equaliser for the Russian side three minutes later.
RB Leipzig 2-0 Instanbul Basaksehir
RB Leipzig had a winning start in Group H after beating Instanbul Basaksehir 2-0 at Red Bull Arena.
Angelino's brace in the first stanza was enough to hand Leipzig the three points in a group that also contains Manchester United and Paris Saint-Germain.