The Black Stars opened their 2022 FIFA World Cup qualifying campaign with a 1-0 win over Ethiopia on Friday and will face Group G rivals South Africa in their second Group G clash on Monday afternoon.
"We invited 32 players because we were aware of the situation, so we are prepared," coach Charles Akonnor said ahead of the match.
"We knew that the England-based players might not come here with us because of the COVID-19 situation and so we were prepared and we knew exactly what will happen so it's not going to be an excuse.
"The whole issue has been a problem, not just me but other national team coaches across the world. Today, you have a plan, tomorrow you wake up and a player has COVID-19 and he cannot join the team.
"Others are not allowed to join the team for the same reason. I don't know if CAF and FIFA are handling the situation well because one may ask, can't we play somewhere else if we cannot bring our players here.
"There are so many questions to answer and it's not making us comfortable. It's so difficult. We come under severe pressure from our nation, we have to win at all cost yet this COVID-19 issue has become a major setback and I don't know if CAF and FIFA are handling the situation very well."
