Chiefs are unbeaten for 18 League games this season, and 23 since the back end of the 2013/14 campaign.
Celtic ended 2014 on a low note when they were beaten 2-1 at Orlando Pirates. The Bloemfontein side has claimed nine points from seven home matches this season.
Phunya Sele Sele are placed 10th on the Absa Premiership log with 20 points from 17 matches.
Celtic secured a return for striker Lerato Manzini during the January transfer window and also signed defenders Marubini Alushavhiwi and Tshepo Rikhotso from Roses United, while Ruben Cloete and Davies Nkausu have moved on.
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Chiefs ended 2014 with a run of three straight wins, the last of which was 1-0 at home over Black Aces. The Soweto giants have claimed 22 points from eight away matches this season.
Amakhosi are placed first on the Absa Premiership log with 46 points from 18 matches.
David Zulu could make his debut following the departure of Kingston Nkhatha to SuperSport United, with Katlego Mphela and Siphelele Mthembu also hoping for a start. George Lebese is not in the squad due to off-field problems.
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In head-to-head stats, Celtic and Chiefs have met in 54 league matches since 1985. Amakhosi have 31 wins compared to 10 for Phunya Sele Sele, while 13 matches have been drawn.
Celtic have won eight of their 26 home matches against Chiefs, suffering eight defeats in the process.
Last 10 League meetings
2009/10: Chiefs 1-1 Celtic (Sibeko; Nthethe)
2010/11: Chiefs 1-0 Celtic (Musona); Celtic 2-2 Chiefs (Spandeel, Bacela; Ncanana, Musona)
2011/12: Celtic 0-0 Chiefs; Chiefs 2-0 Celtic (Baloyi, Majoro)
2012/13: Chiefs 0-0 Celtic; Celtic 0-3 Chiefs (Nkhatha, Tshabalala, Dladla)
2013/14: Celtic 0-0 Chiefs; Chief 3-0 Celtic (Parker, Musona, Buchanan og)
2014/15: Chiefs 1-0 Celtic (Masango)