Mamelodi Sundowns inflicted the heaviest defeat in Al Ahly's CAF competition history in their last Champions League meeting, but still need to prepare with caution.
Sundowns face off against the record eight-time Champions League winners in a repeat of last season's quarter-final that's eternally engraved within the memory of Masandawana fans.
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The 5-0 first-leg victory at the Lucas Masterpieces Moripe Stadium shocked the Red Devils to their core and a 1-0 win in the return leg wasn't enough to spare their blushes.
However, 12 months later the Red Devils, despite their recent Egyptian Super Cup blip at the hands of Zamalek, arrive in formidable form with a newly assembled squad.
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The Weiler effect in full swing
Since Rene Weiler succeeded Uruguayan head coach Martin Lasarte, the man in charge on an eventful afternoon in Tshwane, the Egyptian Premier League champions have looked unstoppable.
Led with the core of Ali Maaloul, Aliou Dieng, Mohamed 'Afsha' Magdy and Nigerian ace Junior Ayayi, the Club of the Century welcomes The Brazilians to Cairo with a perfect league record intact.
After 16 games played this season, the former Anderlecht coach has overseen 16 victories, scoring 46 goals and conceding only three as they steamrolled past every opponent in the Egyptian top-flight.
Meanwhile, Sundowns, who've shown impressive displays of late to maintain a title challenge against Kaizer Chiefs and Orlando Pirates, have won 12 games in 20 fixtures, scoring 29 and conceding 15.
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More than pride at stake in last-eight
While Ahly's domestic record was achieved with a near-perfect season thus far in terms of squad availability, the form guide isn't likely to play as big a role as the motivation and determination to make a statement to the continent.
As one of the most decorated clubs in world football, the thrashing in Attrigeville did much more than provide Ahly's rivals with joy amidst their misery - but also tarnished their impeccable reputation.
And on Saturday afternoon at the Cairo International Stadium, the 41-time Egyptian league champions will see it as step one in restoring themselves to the pinnacle of African football once more.