Mosimane returned to the Ahly dugout on Monday evening after recovering from Covid-19 and masterminded a 4-0 thumping over Al Ittihad of Alexandria in the league.
After the 2-1 Egypt Cup semi-final triumph last season, Mosimane's second win over the side was less of a contest with a dominant display but it seemingly ruffled the feathers of Hassan.
The former Red Devils defender who serves as the Sporting Director of Al Ittihad interrupted the post-match press conference of head coach and brother Hossam to slam Mosimane's abilities.
But the two-time CAF Champions League winner took the statements in his stride when asked about his outburst.
"If we look at what he [Hassan] said, it applies to all the major teams in the world. Real Madrid, Manchester City and PSG but football doesn't work like that," Mosimane said.
"What I know is that football only recognises work and effort and if his words were logical, Al Ahly would have won seven Champions League titles in a row.
"Being Al Ahly doesn't guarantee wins, you need to prepare and work hard but this is his opinion and I respect it."
Since Mosimane's appointment in September, the Club of the Century have won 13 games and drawn one in all competitions.