Atletico Madrid secured their ticket to the round of 16 after seeing off AS Monaco at the Estadio Wanda Metropolitano.
The LaLiga outfit went ahead after just two minutes thanks to an own goal from 17-year-old defender Benoît Badiashile.
The lead was doubled on 24 minutes when Antoine Griezmann bagged his fourth of the campaign.
Monaco did have a chance to pull a goal back in the 82nd minute after being awarded penalty, which resulted in a red card for Stefan Savic, who picked up his second yellow card.
However, Radamel Falcao failed to take advantage after firing wide from 12-yards out as Atletico held on for three points.
Lokomotiv Moscow registered their first win in Group D after defeating Galatasaray 2-0 in Russia.
The home side got the breakthrough goal just before the halftime break, with Grzegorz Krychowiak finding the back of the net.
Vladislav Ignatyev sealed the win for the Russian Premier League outfit in the 54th minute.