Matsatsantsa are in third position, 10 points behind Amakhosi, and have already won the MTN8.
Last week in the Nedbank Cup they were drawn against neighbours Mamelodi Sundowns in the last 32, and Tembo remains confident they can beat Pitso Mosimane's side again in another cup competition.
Speaking after their 2-0 victory over AmaZulu on Sunday, Tembo said they must take things one game at a time to make it possible to win a treble.
"It is one game at a time for us because the gap is big. We should try to focus on picking up points and be consistent," he said.
"We need to notch up wins and see if that gets us closer. It is very important for us to take one game at a time.
"Look, it is football and anything is possible. I think I should give credit to the players for coming out and dishing up [top] performances.
"This [AmaZulu win] was our third game in like eight days. It shows that we are in a good condition physically and mentally.
"We have to keep on going. We have a little bit of a break now because we are only playing on Sunday. That will give us more time."
Tembo then reacted to being drawn against Masandawana, a team they knocked out in the MTN8 semifinals on the way to winning their first trophy this season.
"It is a derby. Tough game. That's how it is. We play Sundowns and Sundowns are a very good team, but we also have a good team that on the day can play and beat anyone," he warned.
"For now we have to focus on our recovery. I could see a lot of tired legs out there from a few players who were coming back from injury. We had to take out Evans Rusike."