Meyiwa was killed on the East Rand of Gauteng over five years ago, yet no arrests or prosecution has been finalised despite multiple teams having been assigned to the case ovet the years.
Meyiwa's older brother Sifiso earlier announced that they have sought the help of the lobby group to deliver justice for the late 'Nzori'.
AfriForum CEO Kalie Kriel on Tuesday confirmed that renowned prosecutor Gerrie Nel, who successfully prosecuted former Paralympian Oscar Pistorius, will now lead a new, thorough investigation.
"I can announce that we were approached by Mr Sifiso Meyiwa and other family members to ask for us to intervene and become involved to try and solve the murder of the late Mr Senzo Meyiwa," announced Kriel at a press briefing.
"We immediately agreed after our meeting yesterday and there was a signed appointment, advocate Gerrie Nel is now officially appointed as the advocate for the Meyiwa family in this matter."
In explaining the process, Kriel added that assistance will be offered to both the SA Police Service and National Prosecutions Authority before they take the route of private prosecution.
"The most important issue here is that the case gets solved. We're not in a position to say we want to prosecute, or we want to do this or that," he explained.
"We want to see a prosecution and get this matter solved. So, we are more than willing to work with the police, because in the first instance it is the police's job to solve this.
"But we have the capacity in our private prosecution's unit, with some of the best investigators that can assist.
"We don't want to take over the police's job, we are saying we're willing to assist and any information that we do find, we will of course share with the police.
"Then the first people to do the prosecution is the NPA, and we would support them in taking this on if they have the facts to prosecute.
"But as Adv Nel has been appointed as advocate for the family, we will monitor the whole process, and in the end if we believe there is a strong case and the NPA does not act then we can go down the route of private prosecution.
"But it's still early days, the first prize is to assist the police with information and make sure the NPA prosecutes, and do it well. Only after that we can decide to privately prosecute."