Amakhosi have been pitted against Bucs in the biggest of the quarterfinal match-ups in the competition after the draw was held in East London on Tuesday night.
The two Soweto giants are set to meet again in the Absa Premiership clash at FNB Stadium on November 9.
According to information gathered by snl24.com/kickoff, the TKO game is likely to be moved to Moses Mabhida Stadium in Durban instead of FNB Stadium due to the Soweto Marathon to be held in Johannesburg on the same weekend.
"The game between Kaizer Chiefs and Orlando Pirates could move to Durban," reveals a source.
"There is the Soweto Marathon on Sunday. The two events cannot be held at the same place on the same weekend."