Atalanta moved up to third spot on the table after hammering ten-man Udinese 7-1 on Sunday afternoon at Gewiss Stadium.
Lucas Muriel's hat-trick was complimented by a brace from Josip IIicic, while Mario Pasalic and Ahmad Traore were also netted for the home side, who ran riot after Nicholas Opoku got a second yellow card and was dismissed just after the half-hour mark.
Stefano Okaka scored what became a consolation goal for the visitors.
Bologna claimed their first win since mid-September after edging struggling Sampdoria 2-1 on Sunday afternoon at Stadio Renato Dall'ara.
Rodrigo Palacio broke the deadlock for the home side three minutes after the break but Manolo Gabbiadini levelled matters for Sampdoria just after the hour-mark. However, Mattia Bani snatched the winner for Bologna 12 minutes before time.
Napoli dropped to fourth on the table after they were held to a 1-1 draw by SPAL on Sunday afternoon at Stadio Paolo Mazza.
Arkadiusz Milik grabbed the lead for Partenopei in the ninth minute but Jasmin Kurtic quickly levelled matters for SPAL seven minutes later.
Simone Zaza netted late for Torino to rescue a 1-1 draw against Cagliari on Sunday afternoon at Stadio Olimpico Grande Torino.
Nahitan Nandez broke the deadlock for the visitors five minutes before the break but Zaza netted with 21 minutes remaining to salvage the share of the spoils for Torino.
Nicolo Zaniolo scored the winner for Roma as they edged AC Milan 2-1 on Sunday evening at Stadio Olimpico.
Edin Dzeko got the breakthrough for Roma with seven minutes remaining of the first stanza but only for Theo Hernandez to equalise for the Rossoneri ten minutes inside the second stanza. However, Zaniolo snatched what was ultimately the winner three minutes thereafter.
Ciro Immobile netted a last minute winner for Lazio in their 2-1 win over ten-man Fiorentina on Sunday evening at Stadio Artemio Franchi.
Joaquin Correa got the opener for Lazio in the 22nd minute but Federico Chiesa levelled matters for the hosts five minutes later. However, Immobile snatched the winner for the visitors a minute before time.