Defender Anele Ngcongca has recovered from a groin injury after missing the first leg in Cairo last weekend.
The former Bafana Bafana international has fully recovered from his injury and in is back in contention for the starting line-up at Lucas Moripe Stadium.
Sundowns coach Pitso Mosimane has confirmed the return of Ngcongca.
"Anele has recovered from injury. We have a proper right-back now," he said.
Meanwhile, there is another boost for the club after 34-year-old captain Hlompho Kekana signed a new four-year contract to keep him at the club until 2024.