Arsenal 2-0 Manchester United
Arsenal gave Mikel Arteta his first win in charge after defeating Manchester United 2-0 on Wednesday night.
Nicolas Pepe got the scoring up and running after eight minutes with a neat finish into the far corner, before Sokratis Papastathopoulos volleyed home the second goal just before the break.
As a result, the Gunners move in to the top half of the table, while United four points behind fourth-placed Chelsea in fifth.
Manchester City 2-1 Everton
Manchester City registered back-to-back wins in the Premier League with a 2-1 triumph over Everton.
After Phil Foden's early goal was ruled out by the Video Assistant Referee, Gabriel Jesus bagged a brace in the second for the Citizens, while Richarlison netted a late consolation for the Toffees.
West Ham United 4-0 Bournemouth
David Moyes made winning return as West Ham United manager after his charges thumped Bournemouth 4-0 at the London Stadium.
Hammers captain Mark Noble bagged a brace while Sebastian Haller and Felipe Anderson also added their names to the scoresheet.
Norwich City 1-1 Crystal Palace
Norwich City were unable to improve their situation at the bottom after a 1-1 draw against Crystal Palace.
Todd Cantwell looked to have sealed a win with his fourth-minute strike, but Palace got the equaliser through Conor Wickham's strike with the help of VAR.
Newcastle United 0-3 Leicester City
Leicester City proved too strong for Newcastle United after romping to a 3-0 win at St James' Park.
Ayoze Perez, James Maddison and Hamza Choudhury secured the goals for the Foxes, who were without Jamie Vardy for a second straight game.
Southampton 1-0 Tottenham Hotspur
Tottenham Hotspur dropped points for a second consecutive game after losing 1-0 to Southampton at St Mary's Stadium.
Danny Ings got the game's only goal in the 17th minute to take his tally to 13 goals for the season.
Watford 2-1 Wolverhampton Wanderers
Watford continued their push towards safety with a 2-1 victory over Wolverhampton Wanders.
Gerard Deulofeu and Abdoulaye Doucouré netted for the Hornets, while Pedro Neto's strike for Wolves proved to be nothing more than a consolation.
Brighton and Hove Albion 1-1 Chelsea
Brighton claimed their first-ever Premier League point off Chelsea thanks to a superb late equaliser at the AMEX Stadium.
Cesar Azpilicueta opened the scoring for the Blues after just 10 minutes with a simple finish from six-yards out.
Second-half substitute Alireza Jahanbakhsh rescued a point for Brighton with a superb overhead-kick that sailed into the bottom corner.
Burnley 1-2 Aston Villa
Aston Villa secured a vital victory in pursuit of staying up after defeating Burnley 2-1 at Villa Park.
After the Video Assistant Referee ruled out Jack Grielish's early goal, Villa went ahead through Wesley on 27 minutes before Grielish doubled the lead just before the break.
Chris Wood pulled a goal back for the hosts in the 80th minute, but Villa were able to hold on for three points.