The quartet will be shipped out to Algeria for a Group B CAF Champions League clash between hosts MC Alger and DR Congo giants TP Mazembe on July 28.
This first leg of the tie will be played in Lubumbashi 11 days earlier.
Mazembe and Alger currently occupy first and second spot in the group respectively, with Morocco's Difaâ Hassani d'el-Jadida and Algeria's ES Setif in third and fourth respectively, after two rounds of fixtures.
SAFA’s technical committee chairperson Natasha Tsichlas has since lauded the four officials for their assignments, and deems it testament to the hard work being put into ensuring South Africa produces top referees and assistants.
“The trust bestowed upon SAFA by CAF is testament of the continuous hard work being put in by the association," Tsichlas told SAFA.
"Refereeing is a critical component of the game that requires constant learning and improvement and, as the association, we strive to be the best exporters of quality referees on the continent."
Gomes was recently crowned PSL Referee of the Season, with Siwele taking home the Assistant Referee of the Season prize at the PSL awards last month.
Meanwhile, Siwele will also be making his FIFA World Cup bow as the only South African representative at the 2018 showpiece in Russia over the next four weeks.