Scott, 29, had only known PSL football with Ajax before joining Slovakian side Slovan Bratislava in January 2016. He spent a year abroad and then penned a contract with Wits as a free agent.
Graham expects a test from the joint-log leaders at Bidvest Stadium, and hopes a positive result can boost their confidence for the derby with Cape Town City on February 11.
Graham told his club's website: "It will my first time playing against Granwald Scott, obviously having played alongside him for a very long time. I am happy for him and what he has achieved, but knowing Bidvest Wits – it is going to be difficult because they are title contenders, especially this season.
"Bidvest Wits have a good squad, knowing coach Gavin [Hunt] and the team he has at his disposal it is going to be a difficult game, they are going to go all in – we will have to match that. For us playing away, it is important that we try and at least get a draw, if we get a chance to win it – we must make sure we don’t let it slip, three points would be the best outcome."
He added: "We have to take it one game at a time, but knowing that the #CapeTownDerby is coming up, things go out of line and the media can almost jump past the Bidvest Wits game. It is really important for us as players to try and get that confidence booster against Bidvest Wits, especially with the second half of the campaign.
"If we do get a positive result it will boost us to go into the derby and hopefully we will get a good result there. It is important to start well and that would obviously reflect positively on the second half of the campaign."