Kaizer Chiefs and Orlando Pirates were drawn to set up a Soweto Derby showdown, which is scheduled to take place at the Moses Mabhida Stadium on November 24.
The fixture has been moved from its traditional home FNB Stadium due to a prior event booking by Stadium Management.
Kick-off of the blockbuster cup clash is set for 15h00.
Meanwhile, defending champions Bidvest Wits will visit Baroka at the Peter Mokaba Stadium for the second semi-final 24 hours later.
CONFIRMATION#TKO2018 Semi-Final Fixtures— Official PSL (@OfficialPSL) November 8, 2018
1. Saturday, 24 November 2018@KaizerChiefs vs @orlandopirates - Moses Mabhida Stadium (15h00)
2. Sunday, 25 November 2018
@Baroka_FC vs @BidvestWits - Peter Mokaba Stadium (15h00)