Strikes from Robert Ng'ambi and Eleazar Rodgers put Chiefs under pressure but they preserved their unbeaten run in the League via goals from Siphiwe Tshabalala and Tefu Mashamaite at Peter Mokaba Stadium.
The result leaves Amakhosi 14 points clear of second-placed champions Mamelodi Sundowns, who have two games in hand ahead of Wednesday's trip to Orlando Pirates.
Stars, who handed Chiefs their only loss of 2014/15 in the Telkom Knockout in October, improve one spot in the standings to 12th at the expense of University of Pretoria.
Dikwena started brightly, as Ng'ambi calmly beat Brilliant Khuzawayo 12 minutes in after being released one-on-one by Solomon Mathe. Mathe laid on the pass after catching Reneilwe Letsholonyane in possession.
Chiefs, though, hit back four minutes later, as Tshabalala steered in a cross from overlapping left-back Tsepo Masilela, with goalkeeper Kabelo Dambe punished for failing to gather the delivery.
Both teams threatened afterwards, but the visitors made it count on the stroke of half-time as Rodgers reacted first to slot home a loose ball in the box following a miscued shot from teammate Thabiso Semenya.
The second period saw chances at either end, with Dambe notably making two top saves to foil Kingston Nkhatha and keep out a deflected effort from George Maluleka.
However, Dambe was beaten in the 62nd minute when Mashamaite rose impressively to nod in a telling cross from the right by Tshabalala.
Allan Freese's side nearly snatched the points late on but substitute Mogakolodi Ngele, on for Ng'ambi, had a low shot on the turn parried away by Khuzwayo.