Maritzburg take on Pirates at Orlando Stadium tonight (19h30) having won the reverse fixture 2-1 at Harry Gwala Stadium on December 13.
United are eighth in the standings with 26 points from 22 matches - three points more than Bucs, who have a game in hand but are just three points above the drop zone.
Kadodia backs interim coach Fadlu Davids to get a result in Soweto.
"You must understand there'll be changes from Pirates. Pirates cannot sit where they are, let's be straight about that," Kadodia tells KickOff.com.
"Because if Pirates lose to us obviously they'll be sitting in a relegation dog fight. Obviously it's going to be a very hard-fought game and Fadlu [Davids] will come with his tactical plan. We just hope that we are going to the game to play a fair game.
"But I'm very confident that Fadlu will prepare his team well and fight for the points in Joburg."
The visitors are without one of their key performers in Kwanda Mngonyama, who is suspended after receiving a fourth caution in the 2-1 win over Ajax Cape Town last time out.
Meanwhile, Kadodia is impressed with how Davids has fared in the hotseat. Davids recently took over the reins from Roger de Sa, while he also did so in November when Ernst Middendorp quit the club. He has recorded three wins and three victories in his six games in charge.
"I think Fadlu has given what we needed most and the players are responding to him well," says Kadodia.
"I think a lot of his mentorship from Ernst Middendorp is paying off, technical awareness and his motivation to the team, you can see the dream.
"That's where the difference between Fadlu and in our last six games. You can see the new lease of life, you see the players the way they are approaching the game. We never had that right until now from the beginning of the season.
"But I don't want to put pressure on him. I have to manage him and that is very important, he's still young.
"He has all the calibre and I've got to encourage him to complete his UEFA coaching badge. He's quite determined to do that. I'd like Fadlu to progress well in football and give him the tools to work with."