The nations are battling for Group B honours as both have six points and are level on goal difference heading into this final pool match.
Both sides beat Mauritius 2-0 and Mozambique 1-0.
The country that loses this afternoon's contest could still advance to the semi-finals of the tournament as the best third-placed team.
“We will play to our strengths against Egypt and I believe development of the players is the bigger objective," said Senong ahead of the 15h00 kick-off.
“We are in this tournament to build the next generation of the South African U-20 national team as we have AFCON qualifiers from next year.
“We want a win and we will do our best to win the match, while ensuring that the players enjoy themselves.”
Amajita XI: Kubheka, Mabiliso, Sambo, Mukumela (c), Cupido, Zuke, Matlou, Ngcobo, Mashiane, Mkatshana, Foster.
Subs: Tshabalala, Leaner, Bull, Cross, Modise, Sibiya, Maswanganyi, Ntsabaleng, Mbulu.