The drama was to hit quick and hard for Ajax as Keamogetse Wolff was shown an instant red card for foul language, leaving the Cape Town outfit having to fend with 10 men for 82 minutes.
As a result of the dismissal Aiden Jenniker was brought on for Brent Carelse in the 15th minute, a sacrifice which had to be made by Ajax to ensure extra cover at the back.
The sending off resulted in a rattled Urban Warriors defence, and Manqele should have made it 1-0 when he ran through three defenders, but his acute shot was palmed over by Sander Westerveld.
On 33 minutes Mzikayise Mashaba slotted through a ball to Manqele, who neatly tucked the ball into the back of the net to put his side in the lead.
After the restart the Dutch keeper had to make a low diving save off a Katlego Mashego shot.
Despite being down to 10 men for the majority of the game, the Urban Warriors managed to hold back the Free State Stars attack.
Khama Billiant had the chance to secure a late equaliser, but his shot went wide.
Stars are up to fifth on the log on 35 points, while Ajax remain in seventh on 31.