Ronaldo, 34, grabbed a goal and assist in the 3-0 win over Sassuolo to soar to an 11-point lead in Serie A after Napoli dropped points against Fiorentina.
The five-time Ballon d'Or winner netted his 18th league goal this season as he extended his lead at the summit of the charts but it also marked an iconic record for the Portugal captain.
Cristiano Ronaldo becomes the first player to ever score in 9 consecutive away Serie A matches ????⚽️— Italian Football TV (@IFTVofficial) February 10, 2019
Classic capocannoniere ⚡️ pic.twitter.com/kQa3B3porI
With scoring in his ninth consecutive away game, the former Real Madrid superstar also reached the 20-goal season landmark for the 13th consecutive season.
And after Lionel Messi drew a rare blank for FC Barcelona in LaLiga, Ronaldo moved just three strikes off the Argentina international, who's aiming for a record sixth Golden Shoe title.
Paris Saint-Germain's Kylian Mbappe, however, remains in second spot behind Messi with 19 goals.
Golden Shoe top-three:
1. Lionel Messi (21 goals, 42pts) - FC Barcelona
2. Kylian Mbappe (19 goals, 38pts) - Paris Saint Germain
3. Cristiano Ronaldo (18 goals, 36pts) - Juventus
18 - Cristiano Ronaldo is the Portuguese player that has scored the most goals in a single Serie A campaign. Ascent. pic.twitter.com/cn4p7REYC8— OptaPaolo (@OptaPaolo) February 11, 2019
The Golden shoe race is based on a point metric system based on goals scored and level of the league's competitiveness.
In Spain, England, Italy, Germany and France goals are worth two.
In countries between six and 22 in UEFA's rankings, 1.5, and the rest of the leagues, 1 point.