Amajita and the South Americans face off in the last group stage match on Saturday at Incheon Football Stadium, Korea Republic.
Kickoff is at 20h00 local time (13h00 SA time).
Senong’s charges are yet to register a win after two games, while Uruguay are flying high with six points from two wins: 1-0 over Italy and 2-0 against Japan.
South Africa lost 2-1 and 2-0 to Japan and Italy respectively, and subsequently find themselves bottom of the table, while Uruguay are leading the pack.
“Uruguay is a hard side to beat but it is not impossible. We have been working hard on how to deal with them and I have strong belief that the boys will deliver as expected because we have emphasized to them that they are worthy of being in the World Cup,” said Senong.
“We are all aware it will be a tough day at the office but we have to play for pride. The boys are fully aware of the situation that is why I believe they will come out strongly against Uruguay.
"As matters stand, our world cup run has come to an end but it doesn’t mean we have to make things easy for the opposition – we are going there to fight for victory.
"It would be a great morale booster for the boys if we were to get a win, especially against a high-riding team like Uruguay. It is a fact that the last two results derailed our plans, but it’s all in the past and we have to focus on what’s ahead of us. I am confident we will do well.”
Uruguay is making their 15th appearance at the FIFA U20 World Cup and has been ever present in the last five editions since 2007.
Their best result was in 1997 and 2013 when they came second. They are the current champions of South American Youth Football.
The top two teams of each group and the four best third-placed teams advance to the round of 16
South Africa U20 World Cup history
2009 – Round of 16
2011 – Did not qualify
2013 – Did not qualify
2015 – Did not qualify
2017 – QUALIFIED
3RD APPEARANCE – 2007, 2009, 2017