The Confederation of African Football (CAF) has called an emergency meeting with Kaizer Chiefs, Orlando Pirates, Mamelodi Sundowns and the South African Football Association (SAFA).
On Thursday, Sundowns' scheduled trip to Algiers to face CR Belouizdad was called off due to Covid-19 restrictions in the country.
"The cancellation comes after the Algerian FA requested a postponement due to further medical restrictions in Algeria, whilst Mamelodi Sundowns were preparing for departure to Algeria," Sundowns confirmed.
This follows the recent logistical nightmare for Chiefs, whose fixture with Wydad Casablanca scheduled for last weekend has been postponed four times amid restrictions in Morocco, with the third postponement clashing with an Al Ahly league fixture.
CAF has called an emergency meeting with SAFA and the three teams involved in continental competitions, with Pirates on the cusp of qualifying for the group stage of the Confederation Cup.
"Following some challenges facing South African teams participating in both the Total CAF Champions League and Total CAF Confederation Cup over Covid-19 restrictions, CAF will tomorrow, 19 February 2021 hold an emergency meeting with SAFA and the three South African teams participating in CAF interclub competitions," the statement read.
"The three clubs are: Mamelodi Sundowns FC, Orlando Pirates FC and Kaizer Chiefs. In recent weeks, a number of teams have raised some concerns about travelling to South Africa and also receiving South African teams for interclub competition fixtures amid Covid-19 concerns.
"The purpose of the meeting is an attempt by CAF to find a way forward between all parties concerned."
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