Al Ahly head coach Pitso Mosimane believes all the CAF Champions League group winners will want to avoid them in the quarter-finals.
The record nine-time Champions League winners could face Mamelodi Sundowns or any of the three other group winners in the competition when the draw takes place on 30 April.
Scroll through the gallery above to see Ahly's preparation for Simba on Friday
Tanzanian giants Simba have won Group A ahead of the Red Devils, while Mamelodi Sundowns have secured group B, Kaizer Chiefs, Wydad and Horoya could still top Group C and Esperance look favourites for Group D.
Chiefs face Horoya needing at least a scoring draw in Guinea to advance, while a win, coupled with Petro Atletico beating Wydad in Casablanca - could see Gavin Hunt's side qualify as group winners.
"We lost to Simba SC away from home but we managed to win against AS Vita Club in DR Congo and we secured a draw in Sudan against Al Merrikh to qualify to the quarter-finals," Mosimane said.
"All the teams that topped their groups don't wish to face Al Ahly. We are a strong team and we won the competition on nine occasions. We'll continue our journey to defend our title."
Mosimane's assistant Sami Komsan echoed his statements speaking to the club's official website: "We are the champions of Africa and we are not afraid to face any team; as we are determined to defend our African title."
Ahly are set to face Didier Gomes' side - who have won four games and drawn one - in Cairo on Friday evening looking for a morale-boosting victory before the knock-out stage.