Amakhosi will host the African Champions League finalists in the Premiership at FNB Stadium, with Bucs fresh off a 4-0 demolition of Golden Arrows in the Telkom Knockout semi-finals in midweek.
"We acknowledge that they (Pirates) are a big team and are currently doing well in Africa," Letsholonyane told his club's official website.
"The main focus will be on us as a team. We have ambitions and we also want to achieve results on the day. We are also doing well so far.
"Preparations for the game are going well and I think we will be ready on Saturday.
"We are aware that this is an emotional moment for the supporters. The Amakhosi supporters have always rallied behind us and this time is no difference. We need their support. Even though soccer is an emotional game, patience is required from the supporters.
"There are times when we make mistakes and that doesn’t mean we commit them deliberately. We are always mindful of their support.
"We always work hard to make the supporters proud. In soccer there’s a win or lose and this being our home game we are preparing to take all the three points. If we don’t get max points it doesn’t mean the end of the world."