Bradley Grobler opened the scoring for Matsatsantsa midway through the first stanza at Lucas Moripe Stadium.
However, substitute Rendani Ndou equalised in the 73rd minute soon after coming on to earn a share of the spoils for Rise and Shine.
City started well and took the game to Gordon Igesund’s team and when Maxwell Molala beat two SuperSport defenders the signs were there that the visitors meant business.
Then Dove Wome tested City’s goalkeeper Modiri Marumo but the effort was off target.
But SuperSport’s dominance quickly paid off when Grobler netted from close range to give the home side the lead.
Towards the end of the first half City tried their best to equalise but Ronwen Williams stood strong in goal.
In the second half, Zambian defender Joseph Musonda went in search of a goal but his effort was wide of the target.
Then City took off Puleng Tlolane for Ndou and within one minute of being on the field, Ndou had scored.
Ndou netted with his left foot after good work by Esau Kanyenda.
Jabu Maluleke had a chance for a late winner but he pulled his shot wide of the target.