The trio have experienced conditions in central Africa before, having played a key role in Bucs' march to the CAF Champions League Final last season, which included stop-overs againstAC Leopards and the DRC's TP Mazembe.
Lekgwathi also feels whoever captains Bafana in Pointe Noire will have a big part to play, with Meyiwa handed the armband in the previous Group A games against Sudan and Nigeria due to the injury-enforced absence of Itumeleng Khune.
Lekgwathi told Pirates' official website: “I think we have enough experience in the team to match Congo. They are leading the group and they know how important winning this match will be for them.
“So, from our side, I think Thabo, Senzo and Oupa will play a big role in that match. Those guys have been to Congo and they know some of the players in that team.”
The 38-year-old defender continued: “It was good that the team left on Thursday. It can be difficult staying there for some time, as we had some experiences which were different to what we are used here. But the boys will have to take this game like a normal game.
“There can be no pressure or intimidation. The crowd will be big but we must take it as if we are playing a normal game. We just need to hurt them because we are faster than them going forward.
“If they have to fight, they must fight – Congo is still in Africa so it is not like we are going to Europe or anything like that. There we must play like we are playing here. We are just in a different place but it is still in Africa, so we must fight.
“Another thing is, the team leader on the day, must be very strong. This is crucial match so, we will have to stay calm and fight hard.”