The sides will revive hostilities tonight in the league at Princess Magogo Stadium at 19h30.
Downs won a previous MTN8 meeting 2-0 in August via goals from Sibusiso Vilakazi and Wayne Arendse at Lucas Moripe Stadium, but Mosimane respects Clinton Larsen's outfit.
"Good team, they play well. They gave us a hard time in the first leg in the top eight because they have the speed," Mosimane said of Abafana Bes'thende.
"[Lerato] Lamola is quick, Knox Mutizwa is also powerful, so you got to respect them. And they've got clever wingers who are really good on one-v-ones. You know how Golden Arrows plays, they're very good.
"Their central midfielder with Zimbabwe [Danny Phiri] is very good. They've got a lot of experience players, Golden Arrows. They've been together as a group for a very long time. That team's got a very good understanding and they play well, they play together."
Mosimane expects another riveting contest in Durban after his side's drama-filled 3-3 draw with AmaZulu at King Zwelithini Stadium.
"Probably it's going to be the same as this [game against AmaZulu], a thriller, and we got a thriller on Sunday and it was good for football."
Mosimane's side are on a six-match winless streak in all competitions, with the former Bafana Bafana boss pointing out they are still trying to find their best combinations following an active transfer window.