Mosimane's men have notched up 52 points from 22 games, having moved 10 points clear at the summit with a 2-0 win over neighbours SuperSport United on Tuesday night.
'Jingles' believes another eight points could set his team up for league glory.
"It was important for us to go and enter 50 plus," Mosimane says.
"We are now at 52 and when we enter 56 then the reality will start to strike because now you are going to 60. You know what happens when you reach 60. What does that mean? It means you have enough chances to win the league.
"We needed to enter 50 when we had 40s. I wanted us to reach 50 first. When you have reached 50 plus and you go above 55, it says the marathon is now entering the stadium."
While Mosimane is thrilled with the Tshwane Derby victory, he is mindful the job is far from over.
"Football is a non-believable game. We need to play our next game against Celtic difficult opponent... it's back-to-back from Chicken Inn game to this.
"The boys fought. SuperSport United is a very good team, you can see the structure, the shape is there, it is organised. You understand the profile of the coach, he brought stability. He needs time to change things a little bit.
"For us it is a massive win. Our next two games are very key. Celtic and Cosmos, those two games will give us 57/58 if we win. Then it really starts to say 100 percent that we can be number two. That gives us a chance again to go next year to the Champions League.
"This time we must play Champions League every year, all the time. Every year we need to go to the Champions League. We need to break the ice, it's not going to be easy but we need to play in the Champions League every year until we get used to it.
"But it's encouraging, the boys are fighting. You can see they run, they press. They are not just good football players and talented, they fight, it's good."