Ntuli's agent Mike Makaab met with Twente officials today in Holland where the deal was finalized.
READ: Ntuli gets Dutch boost
The midfielder will join Twente’s reserve side at the start of next season before being promoted to the first team.
Orlando Pirates’ Head of Development, Augasto Palacious, congratulates Ntuli on his new contract in Europe.
"I am very happy for him. He is a product of our development and I went with him to Holland for his trials," Palacious says.
"He is the first player from Pirates’ development sign a professional contract in Europe. We are proud of him. He has always had the ability and potential to succeed in Europe," he adds.