Manuel Lanzini’s strike ended Spurs’ nine-game winning streak at the London Stadium on Friday night and leaves Chelsea with one hand on the Premier League trophy.
Chelsea could be champions before Spurs next kick a ball. Wins against Middlesbrough on Monday and West Brom next Friday would see Antonio Conte’s side create an unassailable advantage.
But Spurs boss Pochettino told Sky Sports: "We are still fighting. It is disappointing with the result, now we wait for the Chelsea result then it's three games ahead to play.
"You all know now it is more difficult to catch Chelsea but we need to try always until the end."
Pochettino admitted Spurs lacked the intensity they had shown in recent games, but rubbished suggestions that the pressure had got to his players.
"I think that it is true that it was a difficult game. If you compare to five days ago against Arsenal, it was a completely different game,” he added.
"It wasn't the same performance we played last week. I think all the players are disappointed about that. There's nothing to say.
“When you lose, OK maybe it's because of the pressure. Maybe because the bad performance. Maybe because many topics you can add and justify why we lost.
"The reality is we didn't score."