AmaBhubesi, who went the first half of the National First Division season unbeaten home and away, have 48 points from 23 league matches and are nine points ahead of second-placed Lidoda Duvha.
With seven league matches to go, Thanda are now close to the finishing line and a win against Jean Francois Luiscito's side today will leave them with one hand on the title as the club seek their return to the Premiership, where they suffered relegated in 2008/09.
When these two sides met in the reserve fixture in December last year, they were not separated as the game finished goalless draw in Limpopo.
However, Sikhakhane, who helped promote Chippa United to the PSL in 2013/14 season, says there will be no special treatment against Leopards but hopes for a maximum points haul this evening.
"I think this game is very important, like any other games that we've played," Sikhakhane tells KickOff.com.
"But there’s nothing special I can say about this game, but what is important is since we are leading them by nine points, that we shouldn't go into our heads, but what is important is to continue to play our normal game.
"We are not under pressure but we are going to play our normal football and see if we can get the maximum points.
"Unfortunately we don't have the calculator to calculate games we need to win right now but what is important is every game we play we need to take it seriously and my players know this.
"We are mathematicians but we take each game we play seriously and see if we get results in that game."
Having lost only once in the NFD this season - away to University of Pretoria in February - Sikhakhane says the support they received, particularly at Umhlathuze Complex, has been invaluable to the team and the priority right now is to not disappoint them when they play at home.
"I think another thing I've seen when we play at home, what we get from supporters, people go there to encourage the players," he adds.
"Because some of the games we played have been tough but we are able to come away with something. I think also our players don't want to disappoint the people from Umhlathuze who come out in numbers."
If AmaBhubesi are promoted at the end of the season, it will be the first time KZN has three teams in the PSL since 2013/14 season when Golden Arrows were relegated.