South Africa lead 2-0 from the first leg in Maseru a fortnight ago and are looking to book their place in the finals in Zambia next February.
The side will be captained by young Orlando Pirates defender Repo Malepe, with Platinum Stars’ Kobamelo Kodisang anchoring the midfield.
BidVest Wits striker Liam Jordan will lead the line, while Mondli Mpoto from SuperSport United will be in goal.
Jordan and Pirates’ Kamohelo Sithole scored the goals in the first leg, with the latter on the bench for the second leg.
SuperSport’s Fagrie Lakay was not considered due to a groin injury.
Amajita XI: Mpoto, Mohamme, Malepe (C), Makumela, Frosler, Mtshweni, Mokoena, Kodisang, Mbatha, Makgalwa, Jordan.
Subs: Johnson, Kammies, Saralina, Mbule, Rambuwane, Sithole, Mayo