Juventus snapped up the five-time Ballon d'Or winner in a reported €105m (R1.65b) deal and Ramos swiftly sent out his message of gratitude for his long-time teammate.
Referring to him by his Spanish nickname of El Bicho, Ramos lauded the achievements an impact the 33-year-old has on the history of Los Blancos
"Cristiano, your goals, your numbers and everything we have won together speak for themselves," he wrote on his official Twitter account.
"You have deserved a prominent place in the history of Real Madrid. The fans will always remember you.
"It's been a pleasure to play by your side, El Bicho. Strong hug and good luck!!"
.@Cristiano, your goals, your numbers and everything we've won together speak for themselves. You have earned a special place in the history of @RealMadrid. As Madridistas we'll remember you always. It's been a pleasure to play alongside you, bicho. Big hig and good luck! ???????????? pic.twitter.com/NaywaDd3gw— Sergio Ramos (@SergioRamos) July 10, 2018