The two sides meet in the quarter-finals, with the added spice being the meeting of current Reds boss Jurgen Klopp against the German side where he made his name.
Dortmund are favourites after their demolition of Tottenham Hotspur, but Reus remaisn weary.
“Should we wane just a few percentage points then we'll be without a chance,” he says. “They have a good team, and especially in attack they have great players.
"We accept the draw. We're professional and hungry for success."
On the meeting with Klopp, Reus addes: “We chuckled when we heard the news because it was clear the old coach will return home. But we directly said that it's not BVB versus Klopp, but rather Dortmund versus Liverpool.”