This follows the injury of Portsmouth striker Benjani Mwaruwari, who will miss the tie.
Zimbabwe, already out of World Cup qualification, need to thump Namibia, the only side they have beaten, in Group 2 and hope that group leaders Kenya complete a double over Guinea by beating the hosts in Conakry.
Kenya are all but assured of getting a place in the next round, leaving Zimbabwe and Guinea to fight for best runners up spot from the 12 groups.
Platinum Stars goalkeeper Tapuwa Kapini is expected to guard the posts ahead of Energy Murambadoro of Wits, with David Kutyauripo, Onismor Bhasera, James Matola and Makonese forming the defence line.
Esrom Nyandoro, Joel Luphahla and Tinashe Nengomasha will play in the problematic midfield, while veteran Orlando Pirates striker, Gilbert Mushangazhike, scorer of a brace that sunk Namibia in the first fixture at Rufaro, will lead the attack.
The Zimbabwe squad is: Goalkeepers: E. Murambadoro, T. Kapini
Defenders: D. Kutyauripo, O. Bhasera, Z. Jambo, Z. Makonese, O. Moyo, J. Matola
Midfielders: E. Nyandoro, T. Nengomasha, C. Matawu, J. Luphahla, O. Karuru, P. Tafirenyika, M. Mwanjali
Strikers: C. Malajila, G. Mushangazhike, Q. Antipas.