The Colombians have been impressive at the global showpiece so far, topping their group before dispatching Uruguay 2-0 in the Last 16 to secure their progression in the tournament.
Up next is five-time champions Brazil, yet coach Jose Pekerman believes the talent on display from both sides will produce an entertaining and even encounter.
"To progress to the semi-finals is a high leap and this is a defining match because both teams will be at their peak of their performances," Colombia’s national boss told the media.
"On both sides, we can observe great players, and when you have great players on both sides of the pitch, the match will be interesting and very even."
Despite having never passed the Last 16 stage at a Mundial before, Pekerman believes his side will not look too much into the past to determine their fate in Brazil.
"Our team always tries to look ahead," he said.
"For Colombia, each match is a new challenge and a new demanding opponent. So we can't look at the past.
“We must play our match, in keeping with what we've done.
“The key is not to feel that there is a favourite. We'll take it as we have taken our matches before."
Pekerman believes his side are on the way up, as he aims to bring success to Colombia now and in the future.
"We always had great talents [in Colombia] but perhaps we were not able to have consistency," he said.
"In football, you have great teams that stand out because they permanently work. They never relax. Weight of history tells these players to come out onto the field and win.
"They have a winning mentality, firstly because of their talents, and also because of their constant work, and they have a conviction to play at the best level.
"We're on that track – it's a learning curve. We still have a long way to go. I know my players will not keep it at this level and will keep improving."
Colombia’s match-up against the Selecao is scheduled for 10pm South African time in Fortaleza.