The Indian Ocean islanders accounted for Mozambique 4-3 on aggregate in the preliminary round, while Amajita along with 15 other African powerhouses were given a bye for that round.
Reunion will be the visitors for the first leg to be played over the weekend of June 27-29 June and will then host Amajita in the return leg a fortnight later.
Should Amajita prevail over Reunion they are due to meet either Gabon or Botswana in the last qualifying round in September/October before the finals in Rwanda.
The Serame Letsoaka coached side has in recent months prepared for the qualifiers by playing in a Four Nations Tournament in Namibia while also holding regular one week training camps.
Amajita, coached by Styles Phumo at the time, failed to qualify for the 2007 finals after being bundled out by Zambia 3-2 on aggregate in the second round.
However, Letsoaka is making sure that he doesn’t leave anything to chance this year and travelled to Reunion to earlier this year to see the opposition play.
The last time that Amajita qualified for the finals was in 2003 when the championship was staged in Burkina Faso.
Meanwhile, the Under-17 team, Amajimbos, will face Malawi in the first of their qualifiers for the 2009 African Under-17 Championships in Algeria.
Amajimbos also received a bye for the preliminary round, but will start their quest to qualify for Algeria in September at home.
In the event that the Teboho Moloi-coached team overcomes Malawi, Amajimbos will face either Zambia or Namibia in the last qualifying round of matches.