The Warriors' hopes of defending their regional crown have been dampened amid fears that the former Kaizer Chiefs talisman will join Czech Republic-based defender Costa Nhamoinesu on the sidelines.
Nhamionsea, who plies his trade for Sparta Prague, was on Wednesday ruled out due to an ankle injury, with team manager Wellington Mpandare confirming they will now be looking at bringing in a replacement.
"Costa is now definitely out. He aggravated an ankle injury and we only established that very late, so we have to now urgently find a replacement for him before we leave for Polokwane," said Mpandare.
“We also have a challenge in that we are restricted to just two players each from the local clubs, in order not to disrupt the domestic [Zimbabwe] PSL programme during the COSAFA tournament, but we will definitely come up with a plan before we leave Harare."
Meanwhile, Musona, who recently penned a four-year deal with Belgian giants Anderlecht, is set to jet into South Africa to have a niggling ankle injury assessed by the national team's medical staff.
Zimbabwe kick off their title defence next Monday with a quarter-final clash against the winners of Group B, which includes Angola, Botswana, Malawi and Mauritius.