The Reds produced a devastating attacking display against the Gunners at Anfield at the start of the season as they clinched a 4-0 win in August, while last season they shot down the Londoners in a 4-3 thriller at the Emirates Stadium.
And, ahead of the Merseysiders’ return to the capital this weekend, Mignolet is expecting another fast-paced attacking display from his team-mates.
The Belgian told Liverpool's official website: "It’s always an exciting fixture. Last year was a crazy game. I think it’s two sides who like to play football and like to attack, so it will be a nice challenge for us.
"[We want] to create chances like we always do but at the same time make sure that with the guys they have in their squad and the quality they’ve got [that we can] stop them. That will be the biggest challenge.
"We can definitely use [last year's win]. Not only [do our forwards have] individual quality but also they are so quick in the counter-attack.
"When we win the ball back, if we can feed them very early, then they can run at the defence.
"I think that’s always difficult to defend when you have to run back toward your own goal. With the speed they’ve got, it’s never easy."