The Gunners cruised through the group stages with just one defeat in their six matches and are amongst the favourites to go deep in the tournament.
Arsenal prove the only English representatives after Everton stumbled out the group stages after managing just four points from their six games.
Some of the more notable picks saw Lyon drawn against Villarreal while Italian giants Napoli will take on German counterparts RB Leipzig
UEFA Europa League last-32 fixtures:
Borussia Dortmund v Atalanta
Nice v Lokomotiv Moscow
FC Copenhagen v Atletico Madrid
Spartak Moscow v Athletic Bilbao
AEK Athens v Dynamo Kiev
Celtic v Zenit St Petersburg
Napoli v RB Leipzig
Red Star Belgrade v CSKA Moscow
Lyon v Villarreal
Real Sociedad v Red Bull Salzburg
Partisan Belgrade v Viktoria Plzen
SC Braga v Lazio
Ludogorets v AC Milan
FC Astana v Sporting Portugal
Ostersunds v Arsenal
Marseille v SC Braga
The first-leg ties will take place February 15 before the return fixtures on February 22.