The draw took place at CAF's headquarters in Cairo on Wednesday afternoon.
Matsatsantsa were drawn in Group D, with TP Mazembe (Congo Brazzaville), Horoya AT (Guinea) and CF Mounana (Gabon).
Dikwena have been drawn in Group B, alongside CS Sfaxien (Tunisia), MC Alger (Algeria) and Mbabane Swallows (Swaziland).
The first round of group fixtures will see Stars host MC Alger, while SuperSport will welcome Horoya on the weekend of May 12-14.
Full draw results:
Group A: FUS Rabat, Club Africain, Rivers United, Kampala CC
Group B: CS Sfaxien, Platinum Stars, MC Alger, Mbabane Swallows
Group C: Zesco United, Recreativo Lobolo, Al Hilal E, Smouha
Group D: TP Mazembe, SuperSport United, Horoya AT, CF Mounana