Ahly had already secured the title and finished the season seven points ahead of Zamalek but Saturday’s match was a chance for Zamalek to win back some pride against their traditional rivals with a first derby win in nine years.
But the game, which again for security reasons was switched away from Cairo and played at the Military Stadium in Suez, proved a sterile affair.
Zamalek had territorial dominance but could not find a breakthrough, wasting two good chances.
Zamalek's skilful playmaker Ayman Hefni was guilty of spurning a golden chance in the 22nd minute when a neat one-two with attacking midfielder Mohamed Ibrahim saw him ghost behind a static defence but he volleyed over the bar.
Substitute Mostafa Fathi miss-hit his shot with the goal at his mercy in stoppage time.
Ahly looked jaded and were content to sit back in the second half and soak up pressure
But they did have a chance before the break when central defender Ahmed Hegazy’s header from a corner was cleared off the line by Zamalek's left-back Adel Gomaa.
Zamalek have now lost six and drawn seven league matches since defeating a second-string Ahly side 2-0 in 2007 in their last derby success.
Both sides will now turn their attention to their Champions League campaigns, with Ahly particularly in a perilous position after suffering two group defeats.
Zamalek host Sundowns in Cairo on Sunday at the Petrosport Stadium.