However, the Natalians are likely to remain in No 1 position by virtue of current goal difference as it is unlikely that this will be a high scoring affair.
The match is scheduled to kick off at 19h30.
In their league opener, Matsatsantsa beat Free State Stars 1-0 at home. Brent Carelse registered the only goal on the day.
Stars kicked off their 2008/09 league season with a 1-0 away victory over AmaZulu. Striker Luis Renteria scored the only goal of the game, handing Miguel Gamondi’s side all three points.
Last season United drew 1-1 with Stars at home and then beat them 2-0 away in the second round fixture.
It will be the 13th meeting between the sides since Platinum Stars hit the top flight in the 2003/04 season. Of the previous 12 games, 10 have been league encounters.
SuperSport have dominated Stars in their head-to-head meetings, winning six of the 12 games and suffering only three defeats. United have also outscored The Tycoons 17 goals to six.
Platinum Stars have never managed an official home victory over SuperSport. They did beat United 7-6 on penalties in a home cup tie back in 2006/07 after a goalless draw, but they have lost all five league games without scoring a single goal.
In the corresponding fixture last season, SuperSport claimed an impressive 2-0 victory that contributed to their run to the Absa Premiership title. Katlego Mashego scored both goals for the visitors.
Liberian forward Anthony Laffor, who missed SuperSport’s first league game due to a concussion he suffered in the second leg of the MTN8 semi-final against Mamelodi Sundowns, will be available for selection and is likely to make his league debut for Matsatsantsa.
2003/04: Stars 0 Supersport 1 (Khoabane) SuperSport 4 (Raselemane, Sibeko, Mokoro 2) Stars 0 Coca Cola Cup 1st Rd – Supersport 0 Stars 2 (Nkosi, Masanabo)
2004/05: Supersport 0 Stars 0 Stars 0 Supersport 1 (Zwane)
2005/06: Supersport 0 Stars 1 (Mashao) Stars 0 Supersport 4 (Zwane 2, Mahlangu, Mphela)
2006/07: Supersport 1 (Mahlangu) Stars 2 (Mmotong, Studzinski) Stars 0 Supersport 3 (Mphela, Klate 2) ABSA Cup quarter final – Stars 0 Supersport 0 – Stars won 7-6 on penalties
2007/08: Supersport 1 (Katza (pen)) Stars 1 (Marumo (pen)) Stars 0 Supersport 2 (Mashego 2 (1 pen))