The courses will take place in Durban, Johannesburg and Cape Town and provide 3 200 places for boys and girls, between the ages of 8 and 17, for coaching by some of the club's leading youth coaches.
These coaches have all previously worked with the club's academy that has, over the past few years, been responsible for the development of first-team players such as Steven Caulker, Jake Livermore and Andros Townsend.
Spurs are renowned around the world for playing entertaining and attacking football, and the club's coaching programme shares this philosophy, coaching players to play the game with the same style and approach as superstars such as Gareth Bale, Mousa Dembele and Emmanuel Adebayor.
Commenting on the announcement of the partnership, Mark Jones, Head of the Global Coaching Programme, said: "This is a fantastic partnership for the club and we are looking forward to working with Investec to deliver these coaching courses across South Africa.
"The club has a long association with South Africa and through our ongoing relationship with SuperSport United we are aware of the huge amount of talent and passion for football that exists across the country.
"Our goal is to deliver the best learning environment possible to encourage and develop the skills and techniques of all those players that attend the courses, whatever their level."
The first course will take place at St David's School, Johannesburg from December 10-14 and will be attended by Tottenham ambassador and former captain Ledley King.
Each course will be run by four professional full-time coaches, who be assisted by several South African coaches.
To find out more information about all the courses taking place across Johannesburg, Durban and Cape Town and for details of how to reserve a place, please go to www.tottenhamhotspur.com/coaching-sa