Kick-off is at 16h00.
The first leg qualifier will be part of a double header at Dobsonville Stadium in which the senior women's national team (Banyana Banyana) play Zimbabwe in a friendly encounter. Kick-off 19h00.
Amajimbos coach Shakes Mashaba is confident of a good result despite having little time to prepare.
The 10th edition of the African Under-17 Youth Championship is scheduled to take place in Morocco from April 13–27, 2013.
The Amajimbos squad has been training at the University of Johannesburg campus grounds since Monday.
South Africa players born between 1996 and 1997 have undergone MRI Scans to comply with CAF regulations.
The results of the scans have been sent through to CAF headquarters for verification ahead of Saturday's match.
Mashaba feels this camp is a good start to grooming future stars.
"Zambia have tough and skilful players that is why we need to focus more on tactical work."
"There is an air of optimism and excitement amongst the players as well as nerves. This is natural," added Mashaba.
The return leg match will be played in Zambia on October 27.