The match kicks off at 8pm.
Pirates won a second successive Treble last season, adding the Telkom Knockout and Premiership titles to the MTN8 they won early in the campaign, and are looking to win the Top 8 Cup for an unprecedented third successive time.
They have retained most of the squad that did duty last year, with Isaac Chansa their only major departure. According to Augusto Palacios, new signings Onyekachi Okonkwo and Takesure Chinyama are not ready for action just yet.
Celtic finished last season in eighth place on the League table, narrowly edging out Ajax Cape Town to ensure a top-half finish and a place in the MTN8.
Phunya Sele Sele have shuffled their squad somewhat, bringing in experienced players such as Dominic Isaacs and Kurt Lentjies, as well as defender Brent Lawler, though the loss of talented defender Erick Mathoho to Kaizer Chiefs was a big blow.
This will be Pirates' 11th match in the MTN8, and they are unbeaten in the tournament since 2009, having won the last two editions. Overall, Bucs have claimed nine Top 8 titles, putting them second on the honours list, behind Kaizer Chiefs, who have 14.
By contrast, Celtic are playing just their third MTN8 match, having been knocked out at the quarter-final stage in the last two seasons by Chiefs and Mamelodi Sundowns, respectively.
Overall, Phunya Sele Sele have one Top 8 title, from 2005.
This MTN8 quarter-final will be the second Top 8 match-up between Bucs and Celtic. Pirates have had the edge in cup matches between the teams down the years, with five wins to Celtic's two, though the Bloemfontein side has twice defeated the Soweto giants on penalties.
In all competitions the teams have met 59 times since 1985, with Pirates again dominating the stats: 32 wins compared to just 11 for Phunya Sele Sele.
Bucs have an excellent home record against Celtic (just two losses from 28 matches down the years) and have won the last eight matches across all competitions in which they have played host to the team in green and white.
The teams’ last meeting was a League match on May 12, at Orlando Stadium, which Pirates won 2-1, with goals from Thulasizwe Mbuyane, Siyabonga Sangweni and Letladi Madubanya.