The Brazilians, fresh from firing in eight goals in their two friendly matches against Mbabane Swallows and Manzini Warriors in Swaziland, will hope to maintain their form when they play Sivutsa Stars in the first semi-final.
The winner of this game will face either Orlando Pirates or Swaziland's Mbabane Swallows, who will battle it out in the other semi-final.
Employing a 3-4-3 formation that favours the use of one central striker, Neeskens will be spoilt for choice in a team that has at its disposal the talents Nyasha Mushekwi, Eleazar Rodgers and Edward Manqele.
Even without the experience of veteran striker Katlego Mphela, who is recovering from injury, Sundowns proved their attacking prowess in Swaziland and will be favourites to progress to the finals of the Mbombela Super Cup.
Sundowns' spokesperson Kabelo Mosito tells KickOff.com that Neeskens will be using the tournament as a trial run with the club now looking to wrap up their off-season preparations.
"So far our preparations have gone according to plan," says Mosito.
"We are very excited about the 4-0 results we achieved in the two matches that we played in Swaziland. But we are more pleased with the fact that a number of our players were able to get a chance to play," Mosito adds.
"The tournament on Sunday will be another very important part of our training. Obviously, the coach will be eager to have a closer look at some of the players that did not get much game time while we were in Swaziland."